RadioimmunoassayResultsfor Phenytoinin Serum Increasedby AbnormallyHighConcentrationsof Free FattyAcidsin ExternalQuality- ControlSamples
نویسنده
چکیده
Amersham International’s kit for radioimmunoassay of phenytoin in serum or plasma has been extensively tested with lyophilized human control sera, and comparison with gasliquid chromatography in a clinical trial gave excellent agreement between the two methods (1). However, unsatisfactory results were obtained by this laboratory during participation in an American quality-control (QC) scheme for antiepileptic drugs. Here, I present the results of our internal investigation into this problem.
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